Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
Laryngoscope. 2011 May;121(5):1092-7. doi: 10.1002/lary.21550.
OBJECTIVES/HYPOTHESIS: To identify regional and specialty differences in the medical treatment of chronic rhinosinusitis (CRS).
Cross-sectional analysis of a national database.
Ambulatory visits for CRS were extracted from the National Ambulatory Medical Care Survey (NAMCS) for years 2005 to 2006. Medication utilization associated with CRS (antibiotics, antihistamines, nasal steroids, and oral steroids) was tabulated for medication class and individual drug. Statistical analyses were conducted to determine variations in medication class and specific drug utilization by U.S. geographic region and physician specialty, specifically primary care physicians (PCP) versus otolaryngologists (ORL).
Among an estimated 36.2 ± 0.3 million visits for CRS (mean age, 36.8 ± 1.4 years; 60.1 ± 1.9% female), the ratio of PCP to ORL visits was 10:1. The percent of clinician visits with prescriptions for antibiotics (47.3 ± 3.0% of overall visits), nasal steroids (10.8 ± 1.4%) and oral steroids (2.8 ± 0.7%) did not vary significantly by geographic region (P = .79,.66, and.34, respectively). Antihistamines were prescribed significantly more often in the South (15.3 ± 3.4% of visits vs. 11.3 ± 1.8% nationally, P = .04). PCPs were significantly more likely to prescribe antibiotics compared to ORLs (53.3 ± 2.9% vs. 27.4 ± 4.2%, respectively, P < .001) and less likely to prescribe both nasal steroids (9.7 ± 1.5% vs. 17.5 ± 2.8%, P = .01) and oral steroids (2.3 ± 0.7% vs. 6.6 ± 2.0%, P = .01). Significant differences existed for specific drugs prescribed according to specialty.
There are significant variations in the outpatient medical treatment of CRS according to geography and specialty. This study highlights the need for evidence-based medical treatment protocols for CRS.
目的/假设:确定慢性鼻-鼻窦炎(CRS)治疗的区域和专业差异。
国家数据库的横断面分析。
从 2005 年至 2006 年的国家门诊医疗调查(NAMCS)中提取 CRS 的门诊就诊情况。列出了与 CRS 相关的药物使用情况(抗生素、抗组胺药、鼻内类固醇和口服类固醇),按药物类别和药物进行了分类。进行了统计分析,以确定美国地理区域和医生专业(初级保健医生[PCP]与耳鼻喉科医生[ORL])之间药物类别和特定药物使用的差异。
在估计有 3620 万±30 万例 CRS 就诊(平均年龄为 36.8±1.4 岁;60.1%±1.9%为女性)中,PCP 与 ORL 就诊的比例为 10:1。抗生素(总体就诊的 47.3%±3.0%)、鼻内类固醇(10.8%±1.4%)和口服类固醇(2.8%±0.7%)处方的临床就诊比例在地域上无显著差异(P=分别为.79、.66 和.34)。抗组胺药在南部的处方比例明显更高(15.3%±3.4%的就诊与全国 11.3%±1.8%的就诊相比,P=0.04)。与 ORL 相比,PCP 开具抗生素的可能性明显更高(分别为 53.3%±2.9%和 27.4%±4.2%,P<.001),开具鼻内类固醇(分别为 9.7%±1.5%和 17.5%±2.8%,P=0.01)和口服类固醇(分别为 2.3%±0.7%和 6.6%±2.0%,P=0.01)的可能性明显更低。根据专业,开具的特定药物也存在显著差异。
根据地理位置和专业,CRS 的门诊治疗存在显著差异。本研究强调了制定 CRS 循证治疗方案的必要性。