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360度结膜移植术治疗犬弥漫性角膜软化症

360-degree conjunctival grafting for management of diffuse keratomalacia in a dog.

作者信息

Pumphrey Stephanie A, Pizzirani Stefano, Pirie Christopher G

机构信息

Tufts Cummings School of Veterinary Medicine, North Grafton, MA, USA.

出版信息

Vet Ophthalmol. 2011 May;14(3):209-13. doi: 10.1111/j.1463-5224.2010.00864.x.

Abstract

We present a report describing use of a 360-degree conjunctival graft for management of progressive keratomalacia refractory to medical treatment in a 5-month-old American Cocker Spaniel. In the dog of this report, the extension of melting to nearly the entire corneal surface limited surgical options. Following surgery and later resection of the graft, the patient is visual with minimal corneal opacity. Numerous corneal grafting techniques have been described in companion animals, but require special materials and may not be possible when melting is extensive. Although older animals or animals with additional corneal pathology may have less ideal outcomes in terms of corneal clarity than the patient of this report, we believe that 360-degree conjunctival grafting offers a viable and cost-effective option for management of cases with extensive keratomalacia that may otherwise have resulted in enucleation.

摘要

我们报告了一例5月龄美国可卡犬的病例,该犬患有进行性角膜软化症,药物治疗无效,我们采用360度结膜移植术进行治疗。在本报告的这只犬中,角膜溶解扩展至几乎整个角膜表面,限制了手术选择。术后及后期切除移植物后,患犬视力良好,角膜混浊轻微。在伴侣动物中已经描述了多种角膜移植技术,但这些技术需要特殊材料,当角膜溶解广泛时可能无法实施。尽管老年动物或患有其他角膜病变的动物在角膜透明度方面的预后可能不如本报告中的患犬理想,但我们认为360度结膜移植术为治疗广泛角膜软化症提供了一种可行且经济有效的选择,否则这些病例可能需要摘除眼球。

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