Department of Healthcare-Associated Infection and Antimicrobial Resistance, HPA Centre for Infections, Colindale, London, UK.
J Antimicrob Chemother. 2011 May;66 Suppl 4:iv43-iv48. doi: 10.1093/jac/dkr076.
Pan-European surveillance of bacteraemia caused by methicillin-resistant Staphylococcus aureus (MRSA) shows it to be a problem affecting all European countries, although there is marked geographical variation in prevalence. Although the proportion of S. aureus bacteraemia due to MRSA is declining in many countries, data from the European Antimicrobial Resistance Surveillance System (EARSS) for 2008 showed that in more than one-third of countries the proportion remained >25%. In contrast to bacteraemia, community-associated MRSA infection in Europe remains relatively uncommon. However, there appears to be an increasing problem involving transmission of MRSA (particularly sequence type 398) from colonized livestock, particularly pigs, to farm workers, abattoir workers and veterinarians who are in contact with such animals. Molecular analysis of isolates of MRSA has shown that there has been spread of only a limited number of MRSA clones in Europe and that many of these clones show geographical clustering due to dissemination through regional healthcare networks. Despite our increasing understanding of the epidemiology of MRSA in Europe, MRSA infections continue to pose a significant public health challenge.
泛欧耐甲氧西林金黄色葡萄球菌（MRSA）菌血症监测显示，MRSA 已成为影响所有欧洲国家的问题，尽管其流行率存在明显的地域差异。尽管许多国家的耐甲氧西林金黄色葡萄球菌菌血症的比例正在下降，但 2008 年欧洲抗菌药物耐药性监测系统（EARSS）的数据显示，超过三分之一的国家该比例仍>25%。与菌血症不同，欧洲社区相关性 MRSA 感染仍然相对少见。然而，似乎越来越多的问题涉及到从定植的牲畜（特别是猪）向与这些动物接触的农场工人、屠宰场工人和兽医传播 MRSA（特别是 398 型）。对耐甲氧西林金黄色葡萄球菌分离株的分子分析表明，欧洲仅传播了有限数量的耐甲氧西林金黄色葡萄球菌克隆，由于通过区域医疗保健网络传播，许多这些克隆显示出地理聚集性。尽管我们对欧洲耐甲氧西林金黄色葡萄球菌的流行病学有了更多的了解，但耐甲氧西林金黄色葡萄球菌感染仍然对公共健康构成重大挑战。
