Department of Biomedical Engineering, Virginia Commonwealth University, Virginia 23284, USA.
Biomicrofluidics. 2011 Mar 30;5(1):13403. doi: 10.1063/1.3567097.
Electrospinning is a process that creates nanofibers through an electrically charged jet of polymer solution or melt. This technique is applicable to virtually every soluble or fusible polymer and is capable of spinning fibers in a variety of shapes and sizes with a wide range of properties to be used in a broad range of biomedical and industrial applications. Electrospinning requires a very simple and economical setup but is an intricate process that depends on several molecular, processing, and technical parameters. This article reviews information on the three stages of the electrospinning process (i.e., jet initiation, elongation, and solidification). Some of the unique properties of the electrospun structures have also been highlighted. This article also illustrates some recent innovations to modify the electrospinning process. The use of electrospun scaffolds in the field of tissue engineering and regenerative medicine has also been described.
静电纺丝是一种通过聚合物溶液或熔体的带电射流来制造纳米纤维的过程。该技术适用于几乎所有可溶或可熔的聚合物,并能够以各种形状和尺寸纺制纤维,具有广泛的性能,可用于广泛的生物医学和工业应用。静电纺丝需要一个非常简单和经济的设置,但它是一个复杂的过程,取决于几个分子、加工和技术参数。本文综述了静电纺丝过程的三个阶段(即射流引发、拉伸和固化)的信息。还强调了一些电纺结构的独特性质。本文还举例说明了一些改进静电纺丝过程的最新创新。静电纺丝支架在组织工程和再生医学领域的应用也有所描述。