Department of Virology, Division of Infectious Disease Control, Norwegian Institute of Public Health, Oslo, Norway.
J Oral Microbiol. 2010 Feb 12;2. doi: 10.3402/jom.v2i0.2127.
The focus has traditionally been on bacteria and fungi when discussing microbiological aspects of oral disease. Viruses are probably more involved in diseases associated with the oral cavity than has been previously thought. The role of several viruses in ulceration is well known, but viruses of the herpes family may play a role in periodontitis, and papillomaviruses are probably involved in oral cancer. This review offers a brief introduction to virology before discussing the role of the more relevant viruses in oral disease. As to clinical application, it is concluded that the anti-herpes medication may, in some cases, be relevant in treating periodontitis, while papillomavirus vaccine would be expected to decrease the prevalence of oral cancer.
在讨论口腔疾病的微生物学方面时,传统上重点关注细菌和真菌。与之前的想法相比,病毒可能更多地参与了与口腔相关的疾病。几种病毒在溃疡中的作用是众所周知的,但疱疹病毒家族的病毒可能在牙周炎中起作用,乳头瘤病毒可能与口腔癌有关。在讨论更相关的病毒在口腔疾病中的作用之前,本文先对病毒学进行了简要介绍。至于临床应用,结论是,在某些情况下,抗病毒药物可能与治疗牙周炎有关,而乳头瘤病毒疫苗有望降低口腔癌的发病率。