Department of Psychiatry, Soroka University Medical Center.
J Trauma Stress. 2011 Jun;24(3):260-7. doi: 10.1002/jts.20635. Epub 2011 Apr 26.
Individuals with posttraumatic stress disorder (PTSD) are haunted by persistent memories of the trauma, but ironically are impaired in memories of daily life. The current set of 4 experiments compared new learning and memory of emotionally neutral content in 2 groups of patients and aged- and education-matched controls: 20 patients diagnosed with chronic posttraumatic stress disorder (C-PTSD) and 20 patients diagnosed with acute stress disorder (ASD). In all experiments, participants studied a list of stimuli pairs (words or pictures) and were then tested for their memory of the items, or for the association between items in each pair. Results indicated that both types of patients showed associative memory impairment compared to a control group, although their item memory performance was relatively intact. Potential mechanisms underlying such associative memory deficits in posttraumatic patients are discussed.
创伤后应激障碍（PTSD）患者被创伤的持续记忆所困扰，但具有讽刺意味的是，他们的日常生活记忆却受损。当前的四组实验比较了两组患者和年龄及教育程度匹配的对照组中新的学习和情绪中性内容的记忆：20 名被诊断患有慢性创伤后应激障碍（C-PTSD）的患者和 20 名被诊断患有急性应激障碍（ASD）的患者。在所有实验中，参与者学习了一对刺激物（单词或图片），然后对他们对物品的记忆或每对物品之间的关联进行测试。结果表明，两种类型的患者与对照组相比，均表现出联想记忆障碍，尽管他们的项目记忆表现相对完整。讨论了创伤后患者出现这种联想记忆缺陷的潜在机制。
