Department of Pediatrics, Maulana Azad Medical College & Lok Nayak Hospital, New Delhi 110002, India.
J Trop Pediatr. 2012 Feb;58(1):74-6. doi: 10.1093/tropej/fmr034. Epub 2011 Apr 27.
Celiac crisis is a rare, life-threatening complication of celiac disease characterized by worsening of clinical symptoms, multiple metabolic derangements and shock. We report an 8-year-old girl with previously undiagnosed celiac disease who presented with flaccid quadriparesis secondary to severe hypokalemia associated with celiac crisis. Diagnosis was expedited by an elevated anti-tissue transglutaminase antibody titer. The patient improved with correction of hypokalemia, corticosteroids and gluten-free diet. In tropical countries such as India, where both acute flaccid paresis and diarrhea are usually of infective etiologies, this rare clinical condition should also be considered in the differential diagnosis of both.
乳糜泻危象是一种罕见的、危及生命的乳糜泻并发症，其特征是临床症状恶化、多种代谢紊乱和休克。我们报告了一例 8 岁女孩，患有先前未诊断的乳糜泻，因严重低钾血症伴乳糜泻危象导致四肢弛缓性瘫痪。由于抗组织转谷氨酰胺酶抗体滴度升高，诊断得以迅速进行。患者通过纠正低钾血症、皮质类固醇和无麸质饮食得到改善。在印度等热带国家，急性弛缓性麻痹和腹泻通常都具有感染性病因，因此在鉴别诊断这两种疾病时，也应该考虑到这种罕见的临床情况。
