伊朗北部心肌梗死患者慢性感染的血清流行病学研究。
The seroepidemiology of the chronic infections in patients with myocardial infarction in North of Iran.
作者信息
Bazzazi Hadi, Ghaemi Ezzat Allah, Ramezani Mohammad Ali
机构信息
Department of Laboratory Sciences, Islamic Azad University, Gorgan Branch, Gorgan, Iran.
出版信息
J Res Med Sci. 2010 Mar;15(2):116-9.
Abstract
BACKGROUND
Recent studies have suggested that chronic infections with Chlamydia pneumoniae (Cpn) and Helicobacter pylori (Hp) may be associated with the risk of Myocardial Infarction (MI).
METHODS
A cross sectional study was conducted on 140 citizens. Seroprevalence was assessed by ELISA tests measuring IgA and IgG antibodies to Cpn and Hp in sera.
RESULTS
Among patients, %11.4 and %90.0 were seropositive for Anti-Cpn IgA and IgG respectively, and also %51.4 and %58.6 were seropositive for Anti-Hp IgA and IgG respectively.
CONCLUSIONS
The present study shows that previous infection to Cpn in patients with MI is important. But there are no significant association between infection with Hp and MI.
摘要
背景
近期研究表明，肺炎衣原体（Cpn）和幽门螺杆菌（Hp）的慢性感染可能与心肌梗死（MI）风险相关。
方法
对140名市民进行了一项横断面研究。通过ELISA试验检测血清中针对Cpn和Hp的IgA和IgG抗体来评估血清阳性率。
结果
在患者中，抗Cpn IgA和IgG的血清阳性率分别为11.4%和90.0%，抗Hp IgA和IgG的血清阳性率分别为51.4%和58.6%。
结论
本研究表明，MI患者既往感染Cpn很重要。但Hp感染与MI之间无显著关联。
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