Venkatramani Ravindra, Keinan Shahar, Balaeff Alexander, Beratan David N
Department of Chemistry, Duke University, Durham, North Carolina 27708.
Coord Chem Rev. 2011 Apr 1;255(7-8):635-648. doi: 10.1016/j.ccr.2010.12.010.
Theoretical studies of charge transport in deoxyribonucleic acid (DNA) and peptide nucleic acid (PNA) indicate that structure and dynamics modulate the charge transfer rates, and that different members of a structural ensemble support different charge transport mechanisms. Here, we review the influences of nucleobase geometry, electronic structure, solvent environment, and thermal conformational fluctuations on the charge transfer mechanism. We describe an emerging framework for understanding the diversity of charge transport mechanisms seen in nucleic acids.
脱氧核糖核酸（DNA）和肽核酸（PNA）中电荷传输的理论研究表明，结构和动力学调节电荷转移速率，并且结构集合中的不同成员支持不同的电荷传输机制。在这里，我们综述了核碱基几何结构、电子结构、溶剂环境和热构象波动对电荷转移机制的影响。我们描述了一个用于理解核酸中电荷传输机制多样性的新兴框架。
