一项教育计划对1型糖尿病青少年糖化血红蛋白（HbA₁c）水平的影响：一项回顾性研究。
The influence of an educational program on the HbA(1c)-level of adolescents with type 1 diabetes mellitus: a retrospective study.
作者信息
Verbeek Sabine, Vos Rimke C, Mul Dick, Houdijk Mieke E C A M
机构信息
Groene Hart Hospital, Gouda, The Netherlands.
出版信息
J Pediatr Endocrinol Metab. 2011;24(1-2):15-9. doi: 10.1515/jpem.2011.104.
OBJECTIVES
Adherence to diabetes management tasks in type 1 diabetes mellitus (T1DM) patients deteriorates during puberty. This causes glycemic dysregulation, which accelerates the development of long-term complications.
METHODS
The data of 25 poorly regulated T1DM-patients were compared before and 3 and 9 months after a psycho-educational program. Data were extracted from patient's records. The psycho-educational program consisted of three sessions for the patients and one for the parents in a 3-month period.
RESULTS
HbA(1c)-levels at baseline (10.0 +/- 0.72%), decreased by 0.65% after 9 months follow-up (p = 0.08). A subgroup of 15 patients showed a clinical significant HbA(1c)-reduction of > or = 0.5% at 9 months follow-up (subgroup A), with a mean reduction of 1.6%.
CONCLUSIONS
These encouraging results show that a psychoeducational program can be of benefit in improving HbA(1c)-levels in poorly regulated adolescents with T1DM. More research with a larger population is necessary to evaluate the value of psycho-educational programs in this age-group.
目的
1型糖尿病（T1DM）患者在青春期时对糖尿病管理任务的依从性会下降。这会导致血糖失调，加速长期并发症的发展。
方法
对25名血糖控制不佳的T1DM患者在参加心理教育项目前以及项目实施3个月和9个月后的资料进行比较。资料从患者记录中提取。心理教育项目在3个月内包括为患者安排的三次课程和为家长安排的一次课程。
结果
基线时糖化血红蛋白（HbA1c）水平为（10.0±0.72%），随访9个月后下降了0.65%（p = 0.08）。15名患者组成的亚组在随访9个月时糖化血红蛋白（HbA1c）有临床显著降低，降低幅度≥0.5%（A亚组），平均降低1.6%。
结论
这些令人鼓舞的结果表明，心理教育项目可能有助于改善血糖控制不佳的青少年T1DM患者的糖化血红蛋白（HbA1c）水平。需要对更多人群进行研究，以评估心理教育项目在该年龄组中的价值。
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