Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, United States.
Gait Posture. 2011 May;34(1):145-7. doi: 10.1016/j.gaitpost.2011.03.020. Epub 2011 Apr 30.
This pilot study investigated the validity of the functional ambulatory profile (FAP) score from the GAITRite electronic pathway in persons with multiple sclerosis (PwMS) who had onset of walking impairment. Thirteen PwMS who had Expanded Disability Status Scale (EDSS) scores of 4.0-6.0 performed four trials on GAITRite™ pathway, and completed a multidimensional walking assessment including performance tests (timed 25 foot walk; T25FW, timed up and go; TUG), self reports of walking ability (Multiple Sclerosis Walking Scale-12; MSWS-12) and function (Late Life Function and Disability Inventory; LL-FDI), and free-living walking behavior (accelerometry). The FAP score correlated strongly with neurological disability (EDSS, ρ=-0.81), walking performance (T25FW, ρ=-0.82; TUG, ρ=-0.88) and self-reported walking function (LL-FDI, ρ=0.81), and moderately with self-reported walking impairment (MSWS-12, ρ=0.49) and free-living walking behavior (accelerometry, ρ=0.52). This suggests that the FAP score is a valid marker of gait impairment in PwMS who have onset of walking impairment.
本初步研究旨在探讨多发性硬化症患者（PwMS）在出现行走障碍时，步态自动分析系统（GAITRite）电子路径下功能活动概况（FAP）评分的有效性。13 名 EDSS 评分为 4.0-6.0 的 PwMS 在 GAITRiteTM 路径上进行了 4 次试验，并完成了多维行走评估，包括运动测试（25 英尺行走计时测试；T25FW、计时起立行走测试；TUG）、行走能力自评（多发性硬化行走量表-12；MSWS-12）和功能（晚年生活功能和残疾指数；LL-FDI），以及自由行走行为（加速度计）。FAP 评分与神经功能障碍（EDSS，ρ=-0.81）、行走表现（T25FW，ρ=-0.82；TUG，ρ=-0.88）和自我报告的行走功能（LL-FDI，ρ=0.81）呈强相关性，与自我报告的行走障碍（MSWS-12，ρ=0.49）和自由行走行为（加速度计，ρ=0.52）呈中度相关性。这表明 FAP 评分是 PwMS 出现行走障碍时步态障碍的有效标志物。
