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口咽和食管表浅鳞状上皮肿瘤窄带成像内镜的研究进展。

Perspectives on narrow-band imaging endoscopy for superficial squamous neoplasms of the orohypopharynx and esophagus.

机构信息

Department of Endoscopy, The Jikei University School of Medicine, Tokyo, Japan.

出版信息

Dig Endosc. 2014 Jan;26 Suppl 1:1-11. doi: 10.1111/den.12220.

DOI:10.1111/den.12220
PMID:24372999
Abstract

BACKGROUND AND AIM

Narrow-band imaging (NBI) is widely available and over the last decade has been applied as a detection and characterization technique for superficial neoplasms of the aerodigestive tract. The aims of the present study were to systematically review clinical trials of NBI endoscopy and to investigate an upgraded NBI system using a novel endoscope for superficial squamous neoplasms in the orohypopharynx and esophagus.

METHODS

Studies on the diagnostic use of NBI endoscopy for superficial squamous neoplasms in the orohypopharynx and esophagus were retrieved from MEDLINE and PubMed and reviewed. An upgraded NBI system using a novel endoscope was investigated with our clinical cases.

RESULTS

In many clinical trials, NBI endoscopy with or without magnification had high diagnostic value for superficial squamousneoplasms in the orohypopharynx and esophagus. An upgraded NBI system can produce a significantly brighter endoscopic view than conventional endoscopes with high-quality magnified images that could be used to diagnose superficial squamous neoplasms.

CONCLUSIONS

NBI endoscopy with or without magnification has diagnostic utility for superficial squamous neoplasms in the orohypopharynx and esophagus. The upgraded NBI endoscopic system is expected to facilitate the use of NBI and magnifying endoscopic diagnosis.

摘要

背景与目的

窄带成像(NBI)已广泛应用,并在过去十年中被用于检测和描述呼吸道和消化道的浅表性肿瘤。本研究旨在系统性回顾 NBI 内镜的临床研究,并研究一种新型内镜的升级 NBI 系统在口咽和食管浅表鳞状上皮肿瘤中的应用。

方法

从 MEDLINE 和 PubMed 中检索并回顾了关于 NBI 内镜在口咽和食管浅表鳞状上皮肿瘤中的诊断应用的研究。我们还对一种新型内镜的升级 NBI 系统进行了临床案例研究。

结果

在许多临床试验中,NBI 内镜联合或不联合放大技术对诊断口咽和食管的浅表鳞状上皮肿瘤具有较高的价值。升级后的 NBI 内镜系统可提供比传统内镜更亮的内镜视野,并能提供高质量的放大图像,可用于诊断浅表鳞状上皮肿瘤。

结论

NBI 内镜联合或不联合放大技术对口咽和食管的浅表鳞状上皮肿瘤具有诊断价值。升级后的 NBI 内镜系统有望促进 NBI 和放大内镜诊断的应用。

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