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在识别体重减轻和维持的预测因素和相关性方面存在问题:对基于行为改变的体重控制疗法的影响。

Problems in identifying predictors and correlates of weight loss and maintenance: implications for weight control therapies based on behaviour change.

机构信息

Slimming World, Alfreton, UK.

出版信息

Obes Rev. 2011 Sep;12(9):688-708. doi: 10.1111/j.1467-789X.2011.00883.x. Epub 2011 Apr 27.

DOI:10.1111/j.1467-789X.2011.00883.x
PMID:21535362
Abstract

Weight management is a dynamic process, with a pre-treatment phase, a treatment (including process) phase and post-treatment maintenance, and where relapse is possible during both the treatment and maintenance. Variability in the statistical power of the studies concerned, heterogeneity in the definitions, the complexity of obesity and treatment success, the constructs and measures used to predict weight loss and maintenance, and an appreciation of who and how many people achieve it, make prediction difficult. In models of weight loss or maintenance: (i) predictors explain up to 20-30% of the variance; (ii) many predictors are the sum of several small constituent variables, each accounting for a smaller proportion of the variance; (iii) correlational or predictive relationships differ across study populations; (iv) inter-individual variability in predictors and correlates of outcomes is high and (v) most of the variance remains unexplained. Greater standardization of predictive constructs and outcome measures, in more clearly defined study populations, tracked longitudinally, is needed to better predict who sustains weight loss. Treatments need to develop a more individualized approach that is sensitive to patients' needs and individual differences, which requires measuring and predicting patterns of intra-individual behaviour variations associated weight loss and its maintenance. This information will help people shape behaviour change solutions to their own lifestyle needs.

摘要

体重管理是一个动态的过程,包括治疗前阶段、治疗(包括治疗过程)阶段和治疗后维持阶段,在治疗和维持过程中都有可能出现复发。相关研究的统计功效存在差异,肥胖和治疗成功的定义存在异质性,用于预测体重减轻和维持的结构和措施复杂,以及对谁和有多少人能够实现目标的认识,这些都使得预测变得困难。在体重减轻或维持的模型中:(i) 预测因素解释了 20-30%的方差;(ii) 许多预测因素是几个小组成变量的总和,每个变量只占方差的一小部分;(iii) 相关或预测关系在不同的研究人群中存在差异;(iv) 个体间预测因素和结果的相关性差异很大;(v) 大部分方差仍然无法解释。需要在更明确界定的研究人群中,通过纵向追踪,对预测结构和结果测量进行更大程度的标准化,以更好地预测哪些人能够维持体重减轻。治疗方法需要发展更个体化的方法,这种方法要敏感于患者的需求和个体差异,这需要测量和预测与体重减轻及其维持相关的个体行为变化模式。这些信息将帮助人们根据自己的生活方式需求塑造行为改变解决方案。

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