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HIV感染者中的代谢综合征及其组成部分。

Metabolic syndrome and its components in HIV-infected individuals.

作者信息

Lauda Laiz Guedes, Mariath Aline Brandão, Grillo Luciane Peter

机构信息

University of Vale do Itajaí, Itajaí, SC, Brazil.

出版信息

Rev Assoc Med Bras (1992). 2011 Mar-Apr;57(2):182-6. doi: 10.1590/s0104-42302011000200016.

DOI:10.1590/s0104-42302011000200016
PMID:21537705
Abstract

OBJECTIVE

To assess the prevalence of metabolic syndrome and its components in HIV infected individuals assisted in a specialized health center in a municipality in the state of Santa Catarina, Brazil.

METHODS

Cross-sectional study comprising 249 individuals (130 men and 119 women), aged 18 to 73 years. Metabolic syndrome was defined according to the National Cholesterol Education Program, as recommended by the Brazilian Society of Cardiology.

RESULTS

Among the individuals who participated in the study, 20.9% had metabolic syndrome - 18.5% of the men and 23.5% of the women, with no statistical association between genders. Twenty seven percent of the individuals had two components of the syndrome. Components most frequently found were those related to lipid profile (low HDL cholesterol and high triglycerides), followed by elevated waist-circumference, altered blood pressure and altered fasting blood glucose. There was a significant association between gender and elevated waist-circumference.

CONCLUSION

The prevalence of metabolic syndrome found in this study possibly reflects the quality of the health services delivered. We highlight the importance of investigating the presence of metabolic syndrome among HIV-infected populations, thus contributing for their survival.

摘要

目的

评估在巴西圣卡塔琳娜州某城市一家专业健康中心接受治疗的HIV感染者中代谢综合征及其各组分的患病率。

方法

横断面研究,纳入249名年龄在18至73岁之间的个体(130名男性和119名女性)。代谢综合征根据巴西心脏病学会推荐的美国国家胆固醇教育计划来定义。

结果

参与研究的个体中,20.9%患有代谢综合征——男性为18.5%,女性为23.5%,性别之间无统计学关联。27%的个体有该综合征的两种组分。最常出现的组分是与血脂谱相关的组分(低高密度脂蛋白胆固醇和高甘油三酯),其次是腰围增加、血压改变和空腹血糖改变。性别与腰围增加之间存在显著关联。

结论

本研究中发现的代谢综合征患病率可能反映了所提供的医疗服务质量。我们强调调查HIV感染人群中代谢综合征存在情况的重要性,从而有助于他们的生存。

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