St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
PLoS One. 2011 Apr 26;6(4):e19311. doi: 10.1371/journal.pone.0019311.
Avian influenza surveillance in Bangladesh has been passive, relying on poultry farmers to report suspected outbreaks of highly pathogenic H5N1 influenza. Here, the results of an active surveillance effort focusing on the live-bird markets are presented. Prevalence of influenza infection in the birds of the live bird markets is 23.0%, which is similar to that in poultry markets in other countries. Nearly all of the isolates (94%) were of the non-pathogenic H9N2 subtype, but viruses of the H1N2, H1N3, H3N6, H4N2, H5N1, and H10N7 subtypes were also observed. The highly pathogenic H5N1-subtype virus was observed at extremely low prevalence in the surveillance samples (0.08%), and we suggest that the current risk of infection for humans in the retail poultry markets in Bangladesh is negligible. However, the high prevalence of the H9 subtype and its potential for interaction with the highly pathogenic H5N1-subtype, i.e., reassortment and attenuation of host morbidity, highlight the importance of active surveillance of the poultry markets.
孟加拉国的禽流感监测一直较为被动，主要依赖家禽养殖户报告高致病性 H5N1 流感疑似疫情。本研究介绍了一项针对活禽市场的主动监测结果。活禽市场禽类中的流感感染率为 23.0%，与其他国家的家禽市场相似。几乎所有分离株（94%）均属于低致病性 H9N2 亚型，但也观察到 H1N2、H1N3、H3N6、H4N2、H5N1 和 H10N7 亚型的病毒。在监测样本中，高致病性 H5N1 亚型病毒的检出率极低（0.08%），这表明当前孟加拉国零售家禽市场中人类感染的风险可以忽略不计。然而，H9 亚型的高流行率及其与高致病性 H5N1 亚型相互作用的潜力，即重配和宿主发病率的衰减，突显了对家禽市场进行主动监测的重要性。
