Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland, Australia.
PLoS One. 2011 Apr 25;6(4):e18566. doi: 10.1371/journal.pone.0018566.
Delusional-like experiences (DLE) are prevalent in the community. Recent community based studies have found that DLE are more common in those with depression and anxiety disorders, and in those with subclinical symptoms of depression and anxiety. Chronic physical disorders are associated with comorbid depression and anxiety; however, there is a lack of evidence about the association of DLE with common physical conditions. The aim of this study was to explore associations between the common physical disorders and DLE using a large population sample.
Subjects were drawn from the Australian National Survey of Mental Health and Wellbeing 2007, a national household survey of 8841 residents aged between 16 and 85 years. The presence of DLE, selected common physical disorders and symptoms were assessed using a modified World Mental Health Composite International Diagnostic Interview (CIDI) schedule. We examined the relationship between DLE, and physical health-related variables using logistic regression, with adjustments for potential confounding factors.
Of the 8771, 776 (8.4%) subjects positively endorsed one or more DLE. Of the six physical disorders examined, only diabetes and arthritis were significantly associated with the endorsement of DLE. Of the seven broad physical symptoms explored, only hearing problems were consistently associated with DLE.
Delusional-like experiences are common in the Australian community, and are associated with selected chronic physical disorders and with impaired hearing. The direction of causality between these variables warrants closer research scrutiny.
类似妄想的体验（DLE）在社区中很普遍。最近的基于社区的研究发现，DLE 在抑郁症和焦虑症患者中更为常见，在有抑郁和焦虑亚临床症状的患者中也更为常见。慢性躯体疾病与共患抑郁和焦虑有关；然而，关于 DLE 与常见躯体状况之间的关联，证据不足。本研究旨在使用大量人群样本探索常见躯体疾病与 DLE 之间的关联。
本研究的对象来自于澳大利亚 2007 年全国心理健康和幸福感调查，这是一项对年龄在 16 至 85 岁之间的 8841 名居民进行的全国家庭调查。使用改良后的世界心理健康综合国际诊断访谈（CIDI）时间表评估 DLE、选定的常见躯体疾病和躯体症状的存在。我们使用逻辑回归检查了 DLE 与与身体健康相关的变量之间的关系，调整了潜在的混杂因素。
在 8771 名受访者中，有 776 名（8.4%）受试者对一个或多个 DLE 表示肯定。在所检查的六种躯体疾病中，只有糖尿病和关节炎与 DLE 的发生显著相关。在所探讨的七个广泛的躯体症状中，只有听力问题与 DLE 始终相关。
类似妄想的体验在澳大利亚社区很常见，与某些慢性躯体疾病和听力受损有关。这些变量之间的因果关系值得更密切的研究关注。
