Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, Florence, Italy.
Eur J Nutr. 2012 Mar;51(2):167-72. doi: 10.1007/s00394-011-0202-7. Epub 2011 May 4.
Adherence to Mediterranean diet has been shown to be associated with a better health and greater survival. The aim of the present study was to identify change-points in the relationship between food groups composing Mediterranean diet and overall mortality.
The population of the Greek EPIC prospective cohort study (23,349 adult men and women in the Greek EPIC sample who had not previously been diagnosed as having cancer, coronary heart disease or diabetes mellitus at enrolment) was analysed. Segmented logistic regression analysis was conducted to examine the association between each of the food groups contributing to the Mediterranean diet score and overall mortality.
This analysis allowed the determination of the following change-points: among men: 1 change-point for vegetables, legumes, cereals, fish and seafood and dairy products and 2 change-points for fruit and nuts, meat and meat products and ethanol; among women: 1 change-point for legumes and fish and seafood and 2 change-points for the remaining food groups. These cut-off points were used to construct an 'a posteriori' score that may be better in capturing the health-promoting potential of the traditional Mediterranean diet.
Identification of change-points in the relationship between components of the Mediterranean diet and mortality can be used to increase the discriminatory ability of a widely used Mediterranean diet score in relation to mortality.
坚持地中海饮食与更好的健康和更高的生存率有关。本研究的目的是确定地中海饮食组成食物组与全因死亡率之间关系的转折点。
分析了希腊 EPIC 前瞻性队列研究的人群（希腊 EPIC 样本中 23349 名成年男女，在入组时没有被诊断患有癌症、冠心病或糖尿病）。进行分段逻辑回归分析，以检查地中海饮食评分中每个贡献食物组与全因死亡率之间的关联。
该分析确定了以下转折点：男性：蔬菜、豆类、谷物、鱼类和海鲜以及乳制品有 1 个转折点，水果和坚果、肉类和肉类产品以及乙醇有 2 个转折点；女性：豆类和鱼类和海鲜有 1 个转折点，其余食物组有 2 个转折点。这些截止值用于构建一个“后验”评分，可能更能捕捉传统地中海饮食的促进健康的潜力。
确定地中海饮食成分与死亡率之间关系的转折点，可以提高广泛使用的地中海饮食评分与死亡率相关的区分能力。
