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酒精对频繁和不频繁暴饮者模拟驾驶的影响。

Alcohol effects on simulated driving in frequent and infrequent binge drinkers.

作者信息

Bernosky-Smith Kimberly A, Shannon Erin E, Roth Alicia J, Liguori Anthony

机构信息

Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston‐Salem, North Carolina 27101, USA.

出版信息

Hum Psychopharmacol. 2011 Apr;26(3):216-23. doi: 10.1002/hup.1195.

DOI:10.1002/hup.1195
PMID:21542027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3161131/
Abstract

OBJECTIVE

Compared with non‐bingers, binge drinkers are more likely to drive while intoxicated. The extent to which binge frequency impacts confidence in driving and subsequent driving impairment is unknown. This study compared the effects of an experimenter‐delivered alcohol binge on subjective impairment and simulated driving ability in female high‐frequency and low‐frequency bingers.

METHODS

Female drinkers were assigned to high‐frequency (n = 30) or low‐frequency (n = 30) binge groups based on their Alcohol Use Questionnaire responses. At 30‐min intervals within a 2‐h period, participants received either a placebo drink (n = 15 per group) or a 0.2 g/kg dose of alcohol (n = 15 per group; cumulative dose 0.8 g/kg). Self‐reported impairment, driving confidence, and simulated driving were then measured.

RESULTS

Self‐reported confidence in driving was significantly lower after alcohol than after placebo in low‐frequency but not highfrequency bingers. Self‐reported impairment and collisions during simulated driving were significantly greater after alcohol than after placebo in both low‐frequency and high‐frequency bingers.

CONCLUSIONS

The impairing effects of a single alcohol binge on driving ability in women are not influenced by binge frequency. However, high binge frequency may be associated with a less cautious approach to post‐binge driving.

摘要

目的

与非暴饮者相比,暴饮者在醉酒状态下更有可能开车。暴饮频率对驾驶信心及随后的驾驶能力损害的影响程度尚不清楚。本研究比较了实验者给予的酒精暴饮对女性高频和低频暴饮者主观损害及模拟驾驶能力的影响。

方法

根据饮酒者酒精使用问卷的回答,将女性饮酒者分为高频暴饮组(n = 30)和低频暴饮组(n = 30)。在2小时内,每隔30分钟,参与者分别饮用安慰剂饮料(每组n = 15)或0.2 g/kg剂量的酒精(每组n = 15;累积剂量0.8 g/kg)。然后测量自我报告的损害、驾驶信心和模拟驾驶情况。

结果

低频暴饮者饮酒后自我报告的驾驶信心显著低于饮用安慰剂后,但高频暴饮者并非如此。低频和高频暴饮者饮酒后自我报告的模拟驾驶中的损害和碰撞情况均显著高于饮用安慰剂后。

结论

单次酒精暴饮对女性驾驶能力的损害作用不受暴饮频率的影响。然而,高暴饮频率可能与暴饮后驾驶时不够谨慎的态度有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a7c/3161131/dcfbbbf96b76/nihms283233f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a7c/3161131/0d8f194dd2bd/nihms283233f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a7c/3161131/759a9ed60567/nihms283233f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a7c/3161131/dcfbbbf96b76/nihms283233f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a7c/3161131/0d8f194dd2bd/nihms283233f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a7c/3161131/759a9ed60567/nihms283233f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a7c/3161131/dcfbbbf96b76/nihms283233f3.jpg

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