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澳大利亚西部和新南威尔士州癌症姑息治疗患者中焦虑和抑郁的流行情况。

The prevalence of anxiety and depression in palliative care patients with cancer in Western Australia and New South Wales.

机构信息

Western Australian Centre for Cancer and Palliative Care and Curtin Institute for Research Innovation.

出版信息

Med J Aust. 2010 Sep 6;193(S5):S44-7. doi: 10.5694/j.1326-5377.2010.tb03927.x.

DOI:10.5694/j.1326-5377.2010.tb03927.x
PMID:21542445
Abstract

OBJECTIVES

To examine the prevalence and predictors of depression and anxiety in palliative care patients with cancer in Western Australia and New South Wales.

DESIGN, SETTING AND PARTICIPANTS: A descriptive study of 266 consecutive patients at a range of inpatient and outpatient settings including home care, hospices, and private and tertiary care hospitals in WA and NSW from 1 March to 30 June 2002.

MAIN OUTCOME MEASURES

Self-reported anxiety and depression using the Hospital Anxiety and Depression Scale (HADS) at a cut-off score of > or = 8 on each subscale (depression and anxiety) for possible cases, and of > or = 11 for probable cases; a cut-off score of > or = 19 was used for probable combined depression and anxiety.

RESULTS

Patients included 200 in WA and 66 in NSW. For the whole sample, 45.8% of patients were possibly depressed and 22.7% probably depressed; 36.9% were possibly anxious and 19.8% probably anxious. About 25% of patients had probable combined depression and anxiety. Logistic regression analyses indicated that past anxiety in the family predicted probable depression, while age, marital status and past depression predicted probable anxiety. Age and past depression predicted probable combined depression and anxiety.

CONCLUSIONS

These findings underscore the need for routine screening for anxiety and depression in palliative care settings, including questions about past personal and family history of anxiety and depression, and the need for a range of interventions and support services.

摘要

目的

在澳大利亚西部和新南威尔士州的癌症姑息治疗患者中,调查抑郁和焦虑的发生率和预测因素。

设计、地点和参与者:这是一项描述性研究,纳入了 2002 年 3 月 1 日至 6 月 30 日期间,来自西澳大利亚州和新南威尔士州的各种住院和门诊环境(包括家庭护理、临终关怀以及私立和三级保健医院)的 266 例连续患者。

主要观察指标

使用医院焦虑和抑郁量表(HADS),以每个亚量表(抑郁和焦虑)的>或= 8 分作为可能病例的临界值,以>或= 11 分作为可能病例的临界值,以>或= 19 分为可能合并抑郁和焦虑的临界值,评估患者的自我报告焦虑和抑郁情况。

结果

患者中,200 例来自西澳大利亚州,66 例来自新南威尔士州。对于整个样本,45.8%的患者可能患有抑郁,22.7%的患者可能患有严重抑郁;36.9%的患者可能患有焦虑,19.8%的患者可能患有严重焦虑。约 25%的患者患有可能合并的抑郁和焦虑。Logistic 回归分析表明,家庭中有过焦虑史可预测可能发生的抑郁,而年龄、婚姻状况和过去的抑郁史则可预测可能发生的焦虑。年龄和过去的抑郁史可预测可能合并的抑郁和焦虑。

结论

这些研究结果强调了在姑息治疗环境中进行焦虑和抑郁常规筛查的必要性,包括询问过去个人和家庭的焦虑和抑郁病史,以及需要一系列干预措施和支持服务。

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