离子二胺铑配合物催化 2-硝基亚乙烯基芳烃的还原 N-杂环化反应。
Ionic diamine rhodium complex catalyzed reductive N-heterocyclization of 2-nitrovinylarenes.
机构信息
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, Ottawa, Canada.
出版信息
J Org Chem. 2011 Jun 3;76(11):4715-20. doi: 10.1021/jo200320k. Epub 2011 May 13.
PMID:21542601
Abstract
Ionic diamine rhodium complex (1) catalyzes the reductive N-cyclization of 2-vinylnitroarenes using carbon monoxide as a reducing agent to afford functionalized indoles. The catalytic system allows direct access to indoles with ester and ketone groups at the 2- or 3-position, in good yields.
摘要
离子二胺铑配合物（1）在一氧化碳作为还原剂的条件下，催化 2-乙烯基硝基芳烃的还原 N-环化反应，生成功能化吲哚。该催化体系可以直接以高产率得到 2-或 3-位带有酯基和酮基的吲哚。
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