Department of Pathology, The American British Cowdray Medical Center, Mexico City DF, Mexico.
Ann Diagn Pathol. 2012 Aug;16(4):288-91. doi: 10.1016/j.anndiagpath.2011.01.004. Epub 2011 May 4.
Hibernomas are rare benign tumors composed of cells reminiscent of brown adipose tissue. In the mammary gland, hibernomas are extraordinary rare, with only 4 cases reported previously. We report the fifth case in a 37-year-old woman who presented with a slowly growing mobile mass in her right breast. A 2.2 cm well-circumscribed lobulated mass was completely removed. The histopathologic analysis showed the full characteristics of the hibernoma. A review of the clinicopathologic features of hibernomas, its relation to brown adipose tissue in humans, and considerations about its histogenesis are made.
褐色脂肪瘤是由类似于棕色脂肪组织的细胞组成的罕见良性肿瘤。在乳腺中,褐色脂肪瘤非常罕见,以前仅报道过 4 例。我们报告了第五例发生在 37 岁女性,其右侧乳房有一个缓慢生长的可移动肿块。完整切除了一个 2.2 厘米边界清楚的分叶状肿块。组织病理学分析显示出褐色脂肪瘤的全部特征。本文回顾了褐色脂肪瘤的临床病理特征,以及其与人类棕色脂肪组织的关系,并对其组织发生进行了探讨。