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乳房单纯性冬眠瘤:对其起源的认识。

Pure hibernoma of the breast: insights about its origins.

机构信息

Department of Pathology, The American British Cowdray Medical Center, Mexico City DF, Mexico.

出版信息

Ann Diagn Pathol. 2012 Aug;16(4):288-91. doi: 10.1016/j.anndiagpath.2011.01.004. Epub 2011 May 4.

DOI:10.1016/j.anndiagpath.2011.01.004
PMID:21546293
Abstract

Hibernomas are rare benign tumors composed of cells reminiscent of brown adipose tissue. In the mammary gland, hibernomas are extraordinary rare, with only 4 cases reported previously. We report the fifth case in a 37-year-old woman who presented with a slowly growing mobile mass in her right breast. A 2.2 cm well-circumscribed lobulated mass was completely removed. The histopathologic analysis showed the full characteristics of the hibernoma. A review of the clinicopathologic features of hibernomas, its relation to brown adipose tissue in humans, and considerations about its histogenesis are made.

摘要

褐色脂肪瘤是由类似于棕色脂肪组织的细胞组成的罕见良性肿瘤。在乳腺中,褐色脂肪瘤非常罕见,以前仅报道过 4 例。我们报告了第五例发生在 37 岁女性,其右侧乳房有一个缓慢生长的可移动肿块。完整切除了一个 2.2 厘米边界清楚的分叶状肿块。组织病理学分析显示出褐色脂肪瘤的全部特征。本文回顾了褐色脂肪瘤的临床病理特征,以及其与人类棕色脂肪组织的关系,并对其组织发生进行了探讨。

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Pure hibernoma of the breast: insights about its origins.乳房单纯性冬眠瘤:对其起源的认识。
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引用本文的文献

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Lipoma-like hibernoma of the breast: A case report and literature review.乳腺脂肪瘤样冬眠瘤:一例报告及文献复习
Radiol Case Rep. 2023 Sep 15;18(11):4176-4181. doi: 10.1016/j.radcr.2023.08.105. eCollection 2023 Nov.
2
Breast hibernoma in a male patient: a rare case report and review of the literature.男性患者的乳腺冬眠瘤:一例罕见病例报告及文献复习
J Surg Case Rep. 2023 May 12;2023(5):rjad239. doi: 10.1093/jscr/rjad239. eCollection 2023 May.
3
Mammary Hibernoma: A Case Report of a Rare Disease.乳腺冬眠瘤:一种罕见疾病的病例报告
Rev Bras Ginecol Obstet. 2018 Apr;40(4):232-234. doi: 10.1055/s-0038-1639500. Epub 2018 Mar 29.
4
A pilot study of FDG PET/CT detects a link between brown adipose tissue and breast cancer.一项 FDG PET/CT 的初步研究发现棕色脂肪组织与乳腺癌之间存在关联。
BMC Cancer. 2014 Feb 25;14:126. doi: 10.1186/1471-2407-14-126.
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Abnormal Mammary Adipose Tissue Environment of Brca1 Mutant Mice Show a Persistent Deposition of Highly Vascularized Multilocular Adipocytes.Brca1突变小鼠异常的乳腺脂肪组织环境显示出高度血管化的多房性脂肪细胞持续沉积。
J Cancer Sci Ther. 2011 Dec 8(Suppl 2). doi: 10.4172/1948-5956.s2-004.