School of Graduate Entry Medicine and Health, University of Nottingham Medical School at Derby, United Kingdom.
Rev Cardiovasc Med. 2011;12(1):13-20. doi: 10.3909/ricm0585.
Cardiorenal syndrome is an umbrella term describing the range of interactions between the heart and kidneys. Commonly, this focuses on the potential for reduced renal function as a consequence of heart disease and the impact of reduced renal functional reserve on the heart. Importantly, these interactions include both consequences of the disease state and those arising from therapeutic interventions directed at the cardiorenal axis. This article focuses on the potential impact of dialysis treatment, which generates intermittent circulatory stress and results in both acute and chronic adverse cardiovascular effects. This largely unappreciated dimension of the cardiorenal interaction in patients with end-stage renal failure is common, associated with a significant increase in mortality, and may be amenable to a variety of therapeutic approaches in this population characterized by particularly significant clinical management challenges.
心脏肾综合征是一个伞式术语，用于描述心脏和肾脏之间的一系列相互作用。通常，这集中在由于心脏病导致的肾功能降低的可能性，以及肾脏功能储备对心脏的影响。重要的是，这些相互作用包括疾病状态的后果和针对心脏肾轴的治疗干预产生的后果。本文重点讨论了透析治疗的潜在影响，透析治疗会产生间歇性循环应激，导致急性和慢性不良心血管效应。在终末期肾衰竭患者中，这种心脏肾相互作用的很大程度上未被认识到的方面很常见，与死亡率的显著增加有关，并且在这个具有特别显著的临床管理挑战的人群中，可以采用多种治疗方法。
