Division of Neurology/Department of Paediatrics, Hospital for Sick Children/University of Toronto, 555 University Avenue, Toronto, Ontario, Canada.
Brain Topogr. 2011 Oct;24(3-4):253-60. doi: 10.1007/s10548-011-0175-0. Epub 2011 Mar 9.
Developmental neuroimaging studies offer a unique opportunity to gain insight into the underpinnings of various cognitive functions by examining age-related changes in brain structure and function. There is an increasing body of neuroimaging literature discussing issues related to testing children in developmental studies (Crone et al. Human Brain Mapping 31:835-837, 2010). These deal with fMRI developmental studies and discuss methods (Luna et al. Human Brain Mapp 31:863-871, 2010), data interpretation (Poldrack Human Brain Mapp 31:872-878, 2010), and theoretical approaches (Karmiloff-Smith Human Brain Mapp 31:934-941, 2010). There has not yet been an equivalent discussion for MEG developmental studies. This paper will address issues specific to data acquisition, analysis, and interpretation for MEG developmental studies.
发展神经影像学研究通过检查大脑结构和功能随年龄的变化,为深入了解各种认知功能的基础提供了独特的机会。越来越多的神经影像学文献讨论了与在发展研究中测试儿童相关的问题(Crone 等人,《人类大脑图谱》31:835-837,2010)。这些文献涉及 fMRI 发展研究,并讨论了方法(Luna 等人,《人类大脑图谱》31:863-871,2010)、数据解释(Poldrack,《人类大脑图谱》31:872-878,2010)和理论方法(Karmiloff-Smith,《人类大脑图谱》31:934-941,2010)。对于 MEG 发展研究,尚未进行类似的讨论。本文将讨论 MEG 发展研究中特定的数据获取、分析和解释问题。