用于线粒体的可穿透细胞膜的亚氨基吖啶荧光染料。
Cell-permeable iminocoumarine-based fluorescent dyes for mitochondria.
机构信息
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, P R China.
出版信息
Org Lett. 2011 Jun 3;13(11):2884-7. doi: 10.1021/ol200908r. Epub 2011 May 6.
PMID:21548645
Abstract
A class of small molecule fluorophores, 2-iminocoumarin-3-carboxamide derivatives, has been developed by a rapid microwave-assisted process. These fluorescent probes are cell membrane permeable with low cytotoxicity and able to selectively stain organelles in living cells.
摘要
一类小分子荧光团，2-亚氨基-3-羧基酰胺衍生物，已通过快速微波辅助过程开发出来。这些荧光探针具有细胞膜通透性、低细胞毒性，并能够选择性地染色活细胞中的细胞器。
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