Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15782, Santiago de, Compostela, Spain.
Centro Andaluz de Nanomedicina y Biotecnología-BIONAND. Parque Tecnológico de Andalucía, c/Severo Ochoa, 35, 29590, Campanillas, Málaga, Spain.
Sci Rep. 2020 Feb 26;10(1):3528. doi: 10.1038/s41598-020-60573-7.
MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of mitochondrial recycling in a variety of situations in living cells. MitoBlue is a unique tool for the study of these processes that will allow the detailed characterization of communication between mitochondria and lysosomes.
MitoBlue 是一种荧光双脒，可以用于轻松监测不同细胞和细胞状态下线粒体降解过程的变化。MitoBlue 染色模式在线粒体染料和重组荧光探针中是独一无二的，允许在活细胞的各种情况下对线粒体回收进行动态研究。MitoBlue 是研究这些过程的独特工具，它将允许对线粒体和溶酶体之间的通讯进行详细表征。
