Löpez-Beltran A, Gaeta J F, Huben R, Croghan G A
Department of Pathology, Roswell Park Memorial Institute, Buffalo, New York.
Urology. 1990 Feb;35(2):164-7. doi: 10.1016/0090-4295(90)80068-x.
A case of malignant phyllodes tumor of the prostate, with clinical course of recurrence and pulmonary metastasis is described in a thirty-eight-year-old man. Histologically the tumor was characterized by a fibrosarcoma-like pattern with adjacent changes of fibroadenoma and phyllodes type of prostatic atypical hyperplasia. The pathology, histogenesis, differential diagnosis, and the role of immunohistochemistry in the diagnosis and demonstration of its components is reviewed.
本文描述了一例38岁男性前列腺恶性叶状肿瘤,其临床病程包括复发和肺转移。组织学上,肿瘤的特征为纤维肉瘤样模式,伴有相邻的纤维腺瘤改变以及前列腺非典型增生的叶状类型。本文对其病理学、组织发生、鉴别诊断以及免疫组织化学在诊断和显示其成分方面的作用进行了综述。