Reese J H, Lombard C M, Krone K, Stamey T A
J Urol. 1987 Sep;138(3):623-6. doi: 10.1016/s0022-5347(17)43280-0.
We report 3 new cases of phyllodes type of atypical prostatic hyperplasia. This lesion is characterized by epithelial and stromal proliferation. Stromal changes are the most characteristic finding in phyllodes type of atypical prostatic hyperplasia, which show atypical cells with enlarged, hyperchromatic sarcomatoid nuclei. Mitotic figures are not present. Although the histological appearance may mimic that of cystosarcoma phyllodes of the breast, this pattern is present only focally or not at all in phyllodes type of atypical prostatic hyperplasia. On computerized tomographic imaging phyllodes type of atypical prostatic hyperplasia has a distinct appearance. These patients can be expected to have a benign clinical course and distant metastases have not been reported. Treatment is by surgical excision as in benign prostatic hyperplasia.
我们报告了3例叶状型非典型前列腺增生的新病例。该病变的特征是上皮和间质增生。间质变化是叶状型非典型前列腺增生最具特征性的表现,可见具有增大、深染的肉瘤样核的非典型细胞。未见核分裂象。尽管其组织学表现可能类似于乳腺叶状囊肉瘤,但这种模式在叶状型非典型前列腺增生中仅局灶性存在或根本不存在。在计算机断层扫描成像中,叶状型非典型前列腺增生有独特的表现。这些患者预计临床病程为良性,尚未有远处转移的报道。治疗方法与良性前列腺增生一样,采用手术切除。