École de psychologie, Université Laval, Québec, Canada.
Menopause. 2011 Sep;18(9):985-93. doi: 10.1097/gme.0b013e31820db6a1.
The aim of this study was to assess longitudinally the relationship between hot flashes and insomnia symptoms in women receiving adjuvant treatments for breast cancer.
Fifty-eight participants completed a 7-day daily diary assessing hot flashes, the Menopause-Specific Quality of Life Questionnaire, and the Insomnia Severity Index, before and after chemotherapy or radiotherapy and at a 3-month follow-up evaluation.
A first canonical correlation analysis (n = 55) revealed a marginally significant relationship between pretreatment versus posttreatment change scores in hot flashes and sleep (R = 0.39), and a second analysis (n = 51) showed a significant relationship between posttreatment and follow-up changes in hot flash activity and sleep (R = 0.59).
These results show that increases in vasomotor symptoms occurring within the few months after the termination of initial adjuvant treatments for breast cancer are significantly associated with concurrent increases in insomnia symptoms and vice versa.
本研究旨在纵向评估接受乳腺癌辅助治疗的女性中热潮红与失眠症状之间的关系。
58 名参与者在化疗或放疗前后以及 3 个月随访评估时完成了为期 7 天的每日日记，评估热潮红、绝经特异性生活质量问卷和失眠严重程度指数。
第一项典型相关分析（n = 55）显示，治疗前与治疗后热潮红与睡眠变化评分之间存在边缘显著关系（R = 0.39），第二项分析（n = 51）显示，治疗后与随访热潮红活动与睡眠变化之间存在显著关系（R = 0.59）。
这些结果表明，乳腺癌初始辅助治疗结束后几个月内血管舒缩症状的增加与同时出现的失眠症状增加显著相关，反之亦然。
