Bansal Cherry, Handa Uma, Mohan Harsh
Department of Pathology, Eras Medical College and Hospital, Hardoi Road, Lucknow, India.
J Cytol. 2011 Jan;28(1):1-6. doi: 10.4103/0970-9371.76940.
To delineate and characterize the cytomorphologic features of pilomatrixoma (PMX) helpful in correct diagnosis of the lesion on fine needle aspiration cytology (FNAC).
Archival records of clinical findings, FNAC and histopathological reports of PMX cases were analyzed. Aspirate findings in 14 cases of PMX were correlated with detailed clinical data and subsequent histopathology on excisional biopsy. Different morphological findings were graded semiquantitatively from 0 to 3+.
The series showed female preponderance, with head and neck being the commonest site. Majority patients had a single tumor with mean size of 1.6 cm. Out of 14 biopsy proven cases of PMX, cytology findings revealed PMX in 7 cases on the basis of ghost cells, groups of basaloid cells, squamous cells in combination with multinucleated giant cells and calcium deposits in a background of debris. The main reasons for erroneous diagnosis were predominance of one component over the others and non-representative aspirated material.
The cytological features of PMX are characteristic and allow a conclusive diagnosis provided the smears are examined keenly bearing in mind the diagnostic traps that can mislead a cytopathologist.
描绘并表征毛母质瘤（PMX）的细胞形态学特征，以有助于在细针穿刺细胞学检查（FNAC）中对该病变进行正确诊断。
分析PMX病例的临床发现、FNAC及组织病理学报告的存档记录。将14例PMX的穿刺结果与详细的临床数据及后续切除活检的组织病理学结果进行关联。对不同的形态学发现从0至3+进行半定量分级。
该系列显示女性居多，头颈部为最常见部位。大多数患者有单个肿瘤，平均大小为1.6厘米。在14例经活检证实的PMX病例中，细胞学检查结果显示，基于鬼影细胞、基底样细胞群、鳞状细胞与多核巨细胞的组合以及碎屑背景中的钙沉积，7例诊断为PMX。误诊的主要原因是一种成分比其他成分占优势以及抽吸材料不具代表性。
PMX的细胞学特征具有特异性，只要在检查涂片时敏锐地注意到可能误导细胞病理学家的诊断陷阱，就能做出确定性诊断。
