Department of Neurology, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Eur J Neurol. 2011 Dec;18(12):1422-5. doi: 10.1111/j.1468-1331.2011.03423.x. Epub 2011 May 7.
Patients with psychogenic amnesia generally suffer from episodic memory deficits associated with an impairment of self-identity. While the first is generally attributed to limbic dysfunction, the latter might be related to posterior parietal cortex.
In a patient with acute repetitive psychogenic amnesia, three different functional investigations (fMRI, electrical-neuroimaging, PET) during both resting-state and a behavioural paradigm testing 'time-travel' showed left posterior parietal activation, unlike in 12 control subjects.
Impairment of self-identity and episodic memory in psychogenic amnesia may be associated with functional alterations of left posterior parietal cortex.
心因性遗忘症患者通常会出现与自我身份识别障碍相关的情景记忆缺陷。前者通常归因于边缘系统功能障碍,而后者可能与顶叶后皮质有关。
在一名急性反复发作的心因性遗忘症患者中,在静息状态和行为范式测试“时间旅行”期间进行的三项不同的功能研究(fMRI、电神经影像学、PET)显示左侧顶叶后皮质激活,与 12 名对照受试者不同。
心因性遗忘症中自我身份识别和情景记忆的损伤可能与左侧顶叶后皮质的功能改变有关。