Epidemic Intelligence Service, Scientific Education and Professional Development Program Office, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Epidemiol Infect. 2012 Feb;140(2):283-9. doi: 10.1017/S0950268811000719. Epub 2011 May 5.
Routine laboratory testing may not detect non-O157 Shiga toxin-producing Escherichia coli (STEC) reliably. Active clinical, epidemiological, environmental health, and laboratory collaboration probably influence successful detection and study of non-O157 STEC infection. We summarized two outbreak investigations in which such coordinated efforts identified non-O157 STEC disease and led to effective control measures. Outbreak 1 involved illness associated with consuming unpasteurized apple cider from a local orchard. Public health personnel were notified by a local hospital; stool specimens from ill persons contained O111 STEC. Outbreak 2 involved bloody diarrhoea at a correctional facility. Public health personnel were notified by the facility infection control officer; O45 STEC was the implicated agent. These reports highlight the ability of non-O157 STEC to cause outbreaks and demonstrate that a coordinated effort by clinicians, infection-control practitioners, clinical diagnostic laboratorians, and public health personnel can lead to effective identification, investigation, and prevention of non-O157 STEC disease.
常规实验室检测可能无法可靠地检测到非 O157 型产志贺毒素大肠杆菌（STEC）。积极的临床、流行病学、环境卫生和实验室合作可能会影响非 O157 STEC 感染的成功检测和研究。我们总结了两起暴发调查，这些协调一致的努力确定了非 O157 STEC 疾病，并采取了有效的控制措施。暴发 1 涉及与食用当地果园未经巴氏消毒的苹果酒有关的疾病。当地医院通知了公共卫生人员；患病者的粪便标本中含有 O111 STEC。暴发 2 涉及一所惩教设施的血性腹泻。设施感染控制官员通知了公共卫生人员；O45 STEC 是受感染的病原体。这些报告强调了非 O157 STEC 引起暴发的能力，并表明临床医生、感染控制从业者、临床诊断实验室人员和公共卫生人员的协调努力可以有效识别、调查和预防非 O157 STEC 疾病。
