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通过分子诊断揭示的感染产志贺毒素大肠杆菌O111后发生的溶血性尿毒症综合征

Hemolytic uremic syndrome following infection with O111 Shiga toxin-producing Escherichia coli revealed through molecular diagnostics.

作者信息

Operario Darwin J, Moonah Shannon, Houpt Eric

机构信息

University of Virginia Health System, Division of Infectious Diseases and International Health, Charlottesville, Virginia, USA.

出版信息

J Clin Microbiol. 2014 Mar;52(3):1003-5. doi: 10.1128/JCM.02855-13. Epub 2013 Dec 26.

DOI:10.1128/JCM.02855-13
PMID:24371241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3957748/
Abstract

We report a case of hemolytic uremic syndrome in a 69-year-old woman due to Shiga toxin-producing Escherichia coli, possibly serotype O111, to illustrate the potentially deleterious implications of a Campylobacter enzyme immunoassay (EIA) result and the increasing importance of molecular testing when conventional methods are limited.

摘要

我们报告一例69岁女性因产志贺毒素大肠杆菌（可能为O111血清型）导致的溶血性尿毒症综合征，以说明弯曲杆菌酶免疫测定（EIA）结果可能产生的有害影响，以及当传统方法有限时分子检测的重要性日益增加。

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Surveillance for foodborne disease outbreaks - United States, 1998-2008.食源性疾病暴发监测 - 美国，1998-2008 年。
MMWR Surveill Summ. 2013 Jun 28;62(2):1-34.
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Current trends in detecting non-O157 Shiga toxin-producing Escherichia coli in food.食品中非 O157 型志贺毒素产生大肠杆菌检测的当前趋势。
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Escherichia coli O104:H4 outbreak--have we learnt a lesson from it?大肠杆菌O104:H4疫情——我们从中吸取教训了吗？
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A laboratory-developed TaqMan Array Card for simultaneous detection of 19 enteropathogens.一种用于同时检测 19 种肠道病原体的实验室开发的 TaqMan 微阵列芯片。
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Rapid detection of Campylobacter antigen by enzyme immunoassay leads to increased positivity rates.酶免疫分析法快速检测空肠弯曲菌抗原可提高阳性率。
J Clin Microbiol. 2013 Feb;51(2):618-20. doi: 10.1128/JCM.02565-12. Epub 2012 Nov 21.
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Use of clustered regularly interspaced short palindromic repeat sequence polymorphisms for specific detection of enterohemorrhagic Escherichia coli strains of serotypes O26:H11, O45:H2, O103:H2, O111:H8, O121:H19, O145:H28, and O157:H7 by real-time PCR.应用成簇规律间隔短回文重复序列多态性实时 PCR 技术特异性检测肠出血性大肠杆菌血清型 O26:H11、O45:H2、O103:H2、O111:H8、O121:H19、O145:H28 和 O157:H7。
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