随机选取的牙源性囊肿中的p63表达
p63 expression in randomized odontogenic cysts.
作者信息
Seyedmajidi Maryam, Shafaee Shahryar, Shafigh Ensieh, Bijani Ali, Hamidi Hamid
机构信息
Department of Oral & Maxillofacial Pathology, Dental Materials Research Center, Dental Faculty, Babol University of Medical Sciences, PO Box 853, Babol, Mazandaran, Iran.
出版信息
Saudi Med J. 2011 May;32(5):463-6.
OBJECTIVE
To find out the immunohistochemical assessment of p63 expression in odontogenic cysts based on the differences among their clinical behaviors.
METHODS
This study was carried out on 34 archival paraffin-embedded specimens of odontogenic cysts. We obtained the specimens from the Pathology Department of Babol University of Medical Sciences, Babol, Iran from March 2003 to February 2008. The specimens comprised 12 dentigerous cysts, 9 radicular cysts, and 13 keratocystic odontogenic tumors (KCOTs). The immunohistochemical technique was performed using the Envision system for evaluation of p63 expression.
RESULTS
The KCOT revealed the highest p63 expression and the differences between the 3 groups was statistically significant.
CONCLUSION
P63 expression might be helpful when identifying cyst types with more aggressive and invasive phenotype.
目的
基于牙源性囊肿临床行为的差异，探讨p63表达的免疫组织化学评估。
方法
本研究对34例牙源性囊肿存档石蜡包埋标本进行。标本于2003年3月至2008年2月取自伊朗巴博尔医科大学病理科。标本包括12例含牙囊肿、9例根尖囊肿和13例牙源性角化囊性瘤（KCOT）。采用Envision系统进行免疫组织化学技术检测p63表达。
结果
KCOT的p63表达最高，三组之间的差异具有统计学意义。
结论
p63表达在识别具有更具侵袭性表型的囊肿类型时可能有帮助。
Zotero 插件