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曲坦类药物能安全用于航空性头痛吗?

Can triptans safely be used for airplane headache?

机构信息

Department of Neurology, Mareşal Çakmak Military Hospital, Erzurum, Turkey.

出版信息

Neurol Sci. 2011 Dec;32(6):1165-9. doi: 10.1007/s10072-011-0603-7. Epub 2011 May 10.

DOI:10.1007/s10072-011-0603-7
PMID:21556868
Abstract

A few cases of airplane headache (AH) have been reported in the literature. Treatment strategies of AHs are also controversial. We followed-up five patients with AH. They were symptom-free during the daytime. Their physical, neurological, and ear-nose-throat examinations were all normal. Blood chemistries, cerebral magnetic resonance imaging, cerebral magnetic resonance imaging angiography, and paranasal sinus tomography studies of the patients were also normal. We preferred triptans because of the possible effect on the mechanism of AH. Patients were recommended to use single-dose of their drugs half an hour prior to flights. All of the patients had a good response to single dose triptan treatment and became headache-free during flights. This is the first study which puts forward the usefulness of the triptans as a safe treatment choice for airplane AH.

摘要

航空性头痛(AH)的病例在文献中有过报道。AH 的治疗策略也存在争议。我们随访了五例 AH 患者。他们白天无症状。体格检查、神经系统检查和耳鼻喉检查均正常。患者的血液化学检查、脑磁共振成像、脑磁共振血管成像和鼻窦 CT 研究也正常。我们首选曲坦类药物,因为它们可能对 AH 的发病机制有影响。我们建议患者在飞行前半小时使用单剂量药物。所有患者对单次剂量曲坦类药物治疗反应良好,在飞行过程中头痛消失。这是第一项提出曲坦类药物作为航空性头痛安全治疗选择的有用性的研究。

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本文引用的文献

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Eletriptan.依来曲普坦。
Expert Opin Drug Metab Toxicol. 2009 Dec;5(12):1587-98. doi: 10.1517/17425250903410226.
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[Airplane headaches--two new cases and a review of the literature].[航空性头痛——两例新病例及文献综述]
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'Bad trips': airplane headache not just in airplanes?“糟糕的旅程”:飞机性头痛并非只在飞机上出现?
Case Rep Neurol. 2021 Jun 14;13(2):375-379. doi: 10.1159/000515571. eCollection 2021 May-Aug.
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Sherpas, Coca Leaves, and Planes: High Altitude and Airplane Headache Review with a Case of Post-LASIK Myopic Shift.夏尔巴人、古柯叶和飞机:高原和航空性头痛综述并附一例 LASIK 术后近视漂移病例
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J Headache Pain. 2017 Aug 16;18(1):84. doi: 10.1186/s10194-017-0788-0.
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Headaches attributed to airplane travel: a Danish survey.归因于航空旅行的头痛:一项丹麦调查。
J Headache Pain. 2016;17:33. doi: 10.1186/s10194-016-0628-7. Epub 2016 Apr 14.
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