Headache Centres, Neurological Division, SS Giovanni e Paolo Hospital, Venice, Italy.
Padua University, Padua, Italy.
Neurol Sci. 2023 Jul;44(7):2547-2549. doi: 10.1007/s10072-023-06756-2. Epub 2023 Mar 22.
Headache attributed to aeroplane travel (AH) is a well-defined nosological entity whose diagnostic criteria have been published in the third provisional International Classification of Headache Disorders (ICHD) and confirmed in the definitive version. Despite the severe intensity of pain, less than half of the AH cases described used medications for preventing the attack. The most frequent prophylactic therapy spontaneously used by sufferers are simple analgesics, non-steroidal anti-inflammatory drugs (NSAIDs), and nasal decongestants, achieving a complete or partial benefit in about 50% of patients. A complete response of AH to fast-acting triptans has been reported. We describe the case of a 37-year-old migrainous woman suffers from AH in about 75% of her flights who preempted the attacks by using a long-acting triptan (frovatriptan). Giving triptans' mechanism of action, an involvement of the trigemino-vascular system in the pathogenesis of AH could be advanced.
与航空旅行相关的头痛 (AH) 是一种明确的疾病实体，其诊断标准已在第三次临时国际头痛疾病分类 (ICHD) 中公布，并在最终版本中得到确认。尽管疼痛强度很大，但不到一半描述的 AH 病例使用药物来预防发作。患者最常自发使用的预防性治疗是简单的镇痛药、非甾体抗炎药 (NSAIDs) 和鼻减充血剂，约 50%的患者能获得完全或部分缓解。已有报道称 AH 对快速作用的曲坦类药物有完全反应。我们描述了一位 37 岁的偏头痛女性病例，她在大约 75%的飞行中都会出现 AH，她通过使用长效曲坦类药物（夫罗曲坦）来预防发作。根据曲坦类药物的作用机制，可以提出三叉神经血管系统在 AH 发病机制中的作用。
