Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Waste Manag Res. 2012 Mar;30(3):217-24. doi: 10.1177/0734242X11404733. Epub 2011 May 9.
Silk is composed of two major proteins, fibroin (fibrous protein) and sericin (globular, gumming protein). Fibroin has been used in textile manufacturing and for several biomaterial applications, whereas sericin is considered a waste material in the textile industry. Sericin has recently been found to activate the proliferation of several cell-lines and has also shown various biological activities. Sericin can form a gel by itself; however, after mixing with other polymers and cross-linking it can form a film or a scaffold with good characteristics that can be used in the cosmetic and pharmaceutical industries. Sericin is proven to cause no immunological responses, which has resulted in a more acceptable material for biological applications.
蚕丝由两种主要蛋白质组成，即丝素（纤维蛋白）和丝胶（球状、胶凝蛋白）。丝素已被用于纺织制造和多种生物材料应用，而丝胶在纺织工业中被视为一种废料。最近发现丝胶可以激活几种细胞系的增殖，并且还表现出各种生物活性。丝胶可以自行形成凝胶；但是，与其他聚合物混合并交联后，它可以形成具有良好特性的薄膜或支架，可用于化妆品和制药行业。丝胶被证明不会引起免疫反应，这使其成为生物应用中更可接受的材料。
