Department of Radiology, Athens Kapodistrian University, Attikon University Hospital, 1 Rimini Str, 12462 Athens, Greece.
Neuroradiology. 2012 Apr;54(4):361-7. doi: 10.1007/s00234-011-0884-9. Epub 2011 May 12.
This is a multi-center, hospital-based study aiming to estimate social factors influencing pre-hospital times of arrival in acute ischemic stroke, with a perspective of finding ways to reduce arrival time and to augment the number of patients eligible for intra-arterial thrombolysis.
Acute ischemic stroke patients who presented at the emergency units of four major general public hospitals were registered. We assessed information concerning demographics, time of presentation, clinical situation, imaging, treatment, and socioeconomic factors. The sample was divided in two sub-samples, based on the time of arrival since onset of symptoms, and was statistically analyzed.
During one calendar year (2005), 907 patients were registered. Among them 34.6% arrived in the first 6 h from symptom onset, 38.7% arrived between 6 and 24 h, 18.1% after 24 h and for 8.6% the time of onset was unknown. Younger age (P = 0.007), transfer with ambulatory service (Ρ = 0.002), living with a mate (Ρ = 0.004), and higher educational level (P < 0.005) were factors which correlated significantly with early arrival at the hospital.
Instructing patients at high risk for stroke to live with a housemate appears beneficial for timely arrival at the hospital. The establishment of dedicated acute stroke call and transportation center should improve the percentage of early arrival. A national information campaign is needed to increase the level of awareness of the population concerning beneficial social behaviors and optimal reaction to symptoms of acute ischemic stroke.
这是一项多中心、基于医院的研究,旨在评估影响急性缺血性脑卒中患者院前到达时间的社会因素,以期找到缩短到达时间和增加适合动脉内溶栓治疗患者数量的方法。
登记在四家主要公立医院急诊就诊的急性缺血性脑卒中患者。我们评估了人口统计学、就诊时间、临床情况、影像学、治疗和社会经济因素方面的信息。根据自症状发作起的到达时间,将样本分为两个亚组,并进行了统计学分析。
在一个日历年内(2005 年),共登记了 907 例患者。其中 34.6%的患者在症状发作后 6 小时内到达,38.7%在 6-24 小时内到达,18.1%在 24 小时后到达,8.6%的发病时间未知。年龄较轻(P=0.007)、由 ambulant service 转运(Ρ=0.002)、与配偶同住(Ρ=0.004)和受教育程度较高(P<0.005)是与早期到达医院相关的显著因素。
指导高卒中风险患者与配偶同住对及时到达医院有益。建立专门的急性脑卒中呼叫和转运中心应能提高早期到达的比例。需要开展全国性的宣传运动,提高公众对有益的社会行为和对急性缺血性脑卒中症状的最佳反应的认识水平。