Saceleanu Vicentiu Mircea, Toader Corneliu, Ples Horia, Covache-Busuioc Razvan-Adrian, Costin Horia Petre, Bratu Bogdan-Gabriel, Dumitrascu David-Ioan, Bordeianu Andrei, Corlatescu Antonio Daniel, Ciurea Alexandru Vlad
Neurosurgery Department, Sibiu County Emergency Hospital, 550245 Sibiu, Romania.
Neurosurgery Department, "Lucian Blaga" University of Medicine, 550024 Sibiu, Romania.
Biomedicines. 2023 Sep 23;11(10):2617. doi: 10.3390/biomedicines11102617.
Among the high prevalence of cerebrovascular diseases nowadays, acute ischemic stroke stands out, representing a significant worldwide health issue with important socio-economic implications. Prompt diagnosis and intervention are important milestones for the management of this multifaceted pathology, making understanding the various stroke-onset symptoms crucial. A key role in acute ischemic stroke management is emphasizing the essential role of a multi-disciplinary team, therefore, increasing the efficiency of recognition and treatment. Neuroimaging and neuroradiology have evolved dramatically over the years, with multiple approaches that provide a higher understanding of the morphological aspects as well as timely recognition of cerebral artery occlusions for effective therapy planning. Regarding the treatment matter, the pharmacological approach, particularly fibrinolytic therapy, has its merits and challenges. Endovascular thrombectomy, a game-changer in stroke management, has witnessed significant advances, with technologies like stent retrievers and aspiration catheters playing pivotal roles. For select patients, combining pharmacological and endovascular strategies offers evidence-backed benefits. The aim of our comprehensive study on acute ischemic stroke is to efficiently compare the current therapies, recognize novel possibilities from the literature, and describe the state of the art in the interdisciplinary approach to acute ischemic stroke. As we aspire for holistic patient management, the emphasis is not just on medical intervention but also on physical therapy, mental health, and community engagement. The future holds promising innovations, with artificial intelligence poised to reshape stroke diagnostics and treatments. Bridging the gap between groundbreaking research and clinical practice remains a challenge, urging continuous collaboration and research.
在当今脑血管疾病高发病率的背景下，急性缺血性中风尤为突出，它是一个重大的全球性健康问题，具有重要的社会经济影响。及时诊断和干预是管理这种多方面病理状况的重要里程碑，因此了解各种中风发作症状至关重要。多学科团队在急性缺血性中风管理中发挥着关键作用，从而提高识别和治疗的效率。多年来，神经影像学和神经放射学发展迅速，有多种方法可更深入地了解形态学方面，并及时识别脑动脉闭塞以便进行有效的治疗规划。关于治疗方面，药物治疗方法，特别是纤溶疗法，有其优点和挑战。血管内血栓切除术是中风管理中的一个变革者，已经取得了重大进展，诸如支架取栓器和抽吸导管等技术发挥着关键作用。对于特定患者，结合药物和血管内策略具有循证支持的益处。我们对急性缺血性中风进行全面研究的目的是有效比较当前的治疗方法，从文献中识别新的可能性，并描述急性缺血性中风跨学科方法的现状。由于我们追求全面的患者管理，重点不仅在于医疗干预，还在于物理治疗、心理健康和社区参与。未来有充满希望的创新，人工智能有望重塑中风的诊断和治疗。弥合前沿研究与临床实践之间的差距仍然是一项挑战，这促使持续的合作和研究。
