Department of Kinesiology, Faculty of Applied Health Sciences, University of Waterloo, 200 University Ave W., Waterloo, ON N2L 3G1, Canada.
Support Care Cancer. 2012 Apr;20(4):865-73. doi: 10.1007/s00520-011-1175-z. Epub 2011 May 12.
The purpose of this study is to report physical function and quality of life data collected from cancer patients who participated in a supervised exercise intervention at the UW WELL-FIT program over 5 years.
Five hundred seventy-five participants from 18 to 84 years of age (mean, 54 years) were assessed and enrolled in the 24-session program while currently receiving treatment for cancer. Twice weekly, they participated in aerobic exercise, resistance training and stretching exercises for 1 h each time. Pre- and post-assessments were performed to document changes in physical function, while the short form-36 (SF-36) survey assessed changes in quality of life.
Three hundred eighty-six participants completed the program, while 171 withdrew at some point over the 24 sessions. Pre- and post-cardiovascular assessments were performed on 305 (78.4%) participants. There was a significant increase in the maximum work rate attained and significant decreases in heart rate response, systolic blood pressure and rate of perceived exertion at the submaximal level (p < 0.01). The summary component scales of SF-36 (physical and mental) were significantly improved as well as all eight subscales (p < 0.01).
The data collected from this program indicate that a comprehensive physical activity program involving cardiovascular exercise, resistance training and flexibility can significantly improve physical function and various quality of life indices for individuals undergoing treatment for cancer.
本研究旨在报告参加威斯康星州 WELL-FIT 项目监督运动干预的癌症患者的身体功能和生活质量数据,该项目持续了 5 年。
18 至 84 岁(平均 54 岁)的 575 名参与者接受了评估并参加了 24 节课程,同时正在接受癌症治疗。他们每周两次参加有氧运动、阻力训练和伸展运动,每次 1 小时。进行预评估和后评估,以记录身体功能的变化,而简短形式 36(SF-36)调查评估生活质量的变化。
386 名参与者完成了该计划,而 171 名在 24 个课程中的某个时间点退出。对 305 名(78.4%)参与者进行了心血管评估。在达到的最大工作率显著增加,而在亚最大水平的心率反应、收缩压和感知用力率显著降低(p<0.01)。SF-36(身体和精神)的综合分量表以及所有八个子量表(p<0.01)都有显著改善。
该计划收集的数据表明,涉及心血管运动、阻力训练和柔韧性的综合身体活动计划可以显著改善正在接受癌症治疗的个体的身体功能和各种生活质量指标。