IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.
Updates Surg. 2012 Mar;64(1):63-7. doi: 10.1007/s13304-011-0074-7. Epub 2011 May 12.
Fibrosing mediastinitis is a rare benign disorder caused by proliferation of acellular collagen and dense paucicellular fibrous tissue within the mediastinum. Its precise cause, pathogenesis and links to infectious (such as histoplasmosis or tuberculosis) and non-infectious (such as sclerosing cholangitis) diseases remain speculative. Affected patients present signs and symptoms related to obstruction of mediastinal hollow organs, such as large vessels, esophagus and airways. The present study reports the first case described in medical literature of medullar compression by a mediastinal mass penetrated into the spinal canal through neural foramens and causing claudication.
纤维性纵隔炎是一种罕见的良性疾病,由纵隔内无细胞胶原和致密少细胞纤维组织增生引起。其确切病因、发病机制以及与感染(如组织胞浆菌病或结核病)和非感染性疾病(如硬化性胆管炎)的联系仍在推测之中。受影响的患者表现出与纵隔中空器官(如大血管、食管和气道)阻塞相关的体征和症状。本研究报告了首例经神经孔穿透椎管并引起跛行的纵隔肿块压迫骨髓的病例,该病例在医学文献中有所描述。