University of South Florida, College of Medicine, Division of Urogynecology and Pelvic Reconstructive Surgery, Tampa General Hospital, Urogynecology Division, Tampa, Florida, USA.
J Magn Reson Imaging. 2011 Mar;33(3):684-91. doi: 10.1002/jmri.22478.
To describe the inter- and intra-operator reliability of segmentations of female pelvic floor structures.
Three segmentation specialists were asked to segment out the female pelvic structures in 20 MR datasets on three separate occasions. The STAPLE algorithm was used to compute inter- and intra-segmenter agreement of each organ in each dataset. STAPLE computed the sensitivity, specificity, and positive predictive values (PPV) for inter- and intra-segmenter repeatability. These parameters were analyzed using intra-class correlation analysis. Correlation of organ volume to PPV and sensitivity was also computed.
Mean PPV of the segmented organs ranged from 0.82 to 0.99, and sensitivity ranged from 33 to 96%. Intra-class correlation ranged from 0.07 to 0.98 across segmenters. Pearson correlation of volume to sensitivity were significant across organs, ranging from 0.54 to 0.91. Organs with significant correlation of PPV to volume were bladder (-0.69), levator ani (-0.68), and coccyx (-0.63).
Undirected manual segmentation of the pelvic floor organs are adequate for locating the organs, but poor at defining structural boundaries.
描述女性盆底结构分割的组内和组间可靠性。
要求 3 名分割专家在三个不同的场合对 20 个磁共振数据集进行分割。使用 STAPLE 算法计算每个数据集每个器官的组内和组间一致性。STAPLE 计算了组内和组间重复性的灵敏度、特异性和阳性预测值 (PPV)。使用组内相关分析对这些参数进行了分析。还计算了器官体积与 PPV 和灵敏度的相关性。
分割器官的平均 PPV 范围为 0.82 至 0.99，灵敏度范围为 33 至 96%。跨分割器的组内相关系数范围为 0.07 至 0.98。器官体积与灵敏度之间的 Pearson 相关性在各个器官中均具有统计学意义，范围为 0.54 至 0.91。与体积的 PPV 具有显著相关性的器官为膀胱（-0.69）、肛提肌（-0.68）和尾骨（-0.63）。
未定向的手动盆底器官分割足以定位器官，但在定义结构边界方面效果不佳。
