Pôle de Recherche Cardiovasculaire, Institut de Recherche Expérimentale et Cliniques, Université Catholique de Louvain, Brussels, Belgium.
J Am Coll Cardiol. 2011 May 17;57(20):1961-79. doi: 10.1016/j.jacc.2011.02.018.
Cardiovascular diseases are still the primary causes of mortality in the United States and in Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and precipitates an acute vascular event, which is responsible for the high mortality rate. These rupture-prone plaques are called "vulnerable plaques." During the past decades, much effort has been put toward accurately detecting the presence of vulnerable plaques with different imaging techniques. In this review, we provide an overview of the currently available invasive and noninvasive imaging modalities used to detect vulnerable plaques. We will discuss the upcoming challenges in translating these techniques into clinical practice and in assigning them their exact place in the decision-making process.
心血管疾病仍然是美国和西欧的主要死亡原因。动脉血栓形成是由破裂的动脉粥样硬化斑块引发的，并引发急性血管事件，这是导致高死亡率的原因。这些易破裂的斑块被称为“脆弱斑块”。在过去的几十年中，人们投入了大量的精力来使用不同的成像技术准确地检测易损斑块的存在。在这篇综述中，我们概述了目前用于检测易损斑块的有创和无创成像方式。我们将讨论将这些技术转化为临床实践以及在决策过程中为它们分配确切位置所面临的挑战。
