Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Paris, France.
FEMS Microbiol Rev. 2011 Nov;35(6):1035-54. doi: 10.1111/j.1574-6976.2011.00280.x. Epub 2011 Jun 6.
Since their discovery in the early 1980s, viruses that infect the third domain of life, the Archaea, have captivated our attention because of their virions' unusual morphologies and proteins, which lack homologues in extant databases. Moreover, the life cycles of these viruses have unusual features, as revealed by the recent discovery of a novel virus egress mechanism that involves the formation of specific pyramidal structures on the host cell surface. The available data elucidate the particular nature of the archaeal virosphere and shed light on questions concerning the origin and evolution of viruses and cells. In this review, we summarize the current knowledge of archeoviruses, their interaction with hosts and plasmids and their role in the evolution of life.
自 20 世纪 80 年代初发现以来,感染生命第三域(古菌)的病毒因其病毒粒子的异常形态和蛋白质而引起了我们的关注,这些蛋白质在现有的数据库中没有同源物。此外,这些病毒的生命周期具有不寻常的特征,最近发现的一种新型病毒出芽机制揭示了这一点,该机制涉及在宿主细胞表面形成特定的金字塔结构。现有数据阐明了古菌病毒圈的特殊性质,并为有关病毒和细胞的起源和进化的问题提供了线索。在这篇综述中,我们总结了古病毒的最新知识,包括它们与宿主和质粒的相互作用及其在生命进化中的作用。