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功能性消化不良患者的实验室参数和营养状况。

Laboratory parameters and nutritional status in patients with functional dyspepsia.

机构信息

Department of Gastroenterohepatology, Clinical and Hospital Center "Bezanijska Kosa", Belgrade, Serbia.

出版信息

Eur J Intern Med. 2011 Jun;22(3):300-4. doi: 10.1016/j.ejim.2011.01.012. Epub 2011 Feb 15.

DOI:10.1016/j.ejim.2011.01.012
PMID:21570652
Abstract

BACKGROUND

To investigate differences in laboratory markers, nutritional status parameters and eating patterns among newly diagnosed patients with functional dyspepsia.

METHOD

The investigation was performed on 180 newly diagnosed patients with functional dyspepsia, aged 20-79, which were referred to the gastroenterology unit of the Clinical and Hospital Center "Bezanijska Kosa" from April to October 2009. Rome II criteria were used for further classification.

RESULTS

ANOVA Bonferroni post hoc correction outlined that concentrations of serum magnesium and calcium were significantly lower in subjects with ulcer-like dyspepsia, while vitamin B12, glucose and immunoglobulin G level was significantly higher in group with dismotility-like dyspepsia. Statistical analysis revealed that the numbers of meal taken per day were significantly different. There was a statistical trend to skipping meals and to eat fast in patients with ulcer-like and dismotility-like functional dyspepsia when compared with non-specific dyspeptic subjects.

CONCLUSION

Patients with ulcer-like functional dyspepsia suffered from epigastric pain and burning and from heartburn, while persons with dismotility-like dyspepsia were complaining about postprandial fullness, bloating and early satiety. They skipped meals more frequently and avoided intake of certain supplies which, together with eating habits, provoked or emphasized the annoying symptoms.

摘要

背景

研究新诊断功能性消化不良患者的实验室标志物、营养状况参数和饮食模式的差异。

方法

2009 年 4 月至 10 月,对 180 名新诊断的功能性消化不良患者进行了调查,年龄为 20-79 岁,这些患者均来自临床和医院中心“Bezanijska Kosa”的胃肠病学单元。进一步采用罗马 II 标准进行分类。

结果

方差分析 Bonferroni 事后校正指出,溃疡样消化不良患者的血清镁和钙浓度明显降低,而动力障碍样消化不良患者的维生素 B12、葡萄糖和免疫球蛋白 G 水平明显升高。统计分析显示,每天进餐次数有显著差异。与非特异性消化不良患者相比,溃疡样和动力障碍样功能性消化不良患者存在不规律进食和进食过快的趋势。

结论

溃疡样功能性消化不良患者出现上腹痛和烧灼感以及烧心,而动力障碍样消化不良患者则表现为餐后饱胀、腹胀和早饱。他们更频繁地不吃饭,并避免摄入某些食物,这些食物以及饮食习惯会引发或加重恼人的症状。

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