犬胰腺透明腺泡细胞癌呈现出不寻常的黏液样分化。

Canine pancreatic clear acinar cell carcinoma showing an unusual mucinous differentiation.

作者信息

Pavone S, Manuali E, Eleni C, Ferrari A, Bonanno E, Ciorba A

机构信息

Department of Biopathological Science and Hygiene of Animal and Food Production, Faculty of Veterinary Medicine, University of Perugia, Perugia, Italy.

出版信息

J Comp Pathol. 2011 Nov;145(4):355-8. doi: 10.1016/j.jcpa.2011.03.009. Epub 2011 May 14.

DOI:10.1016/j.jcpa.2011.03.009

PMID:21571301

Abstract

A small solitary pancreatic nodule was identified in a 10-year-old mixed breed male dog. Microscopically, the lesion consisted of neoplastic clear acinar cells with diffuse, marked mucin production. Immunohistochemical and ultrastructural investigations confirmed the exocrine acinar origin of the tumour. The tumour was classified as a pancreatic clear acinar cell carcinoma (ACC) showing an unusual mucinous differentiation.

摘要

在一只10岁的混种雄性犬中发现了一个小的孤立性胰腺结节。显微镜下，病变由具有弥漫性、显著粘蛋白产生的肿瘤性透明腺泡细胞组成。免疫组织化学和超微结构研究证实了该肿瘤的外分泌腺泡起源。该肿瘤被分类为胰腺透明腺泡细胞癌（ACC），表现出不寻常的粘液样分化。