Laboratoire de Génétique Moléculaire, Génomique, Microbiologie, Département Microorganismes, Génomes, Environnement, UMR7156 Université de Strasbourg/CNRS, 28 Rue Goethe, 67083 Strasbourg Cedex, France.
Appl Environ Microbiol. 2011 Jul;77(13):4685-92. doi: 10.1128/AEM.02884-10. Epub 2011 May 13.
In this study, new strains were isolated from an environment with elevated arsenic levels, Sainte-Marie-aux-Mines (France), and the diversity of aoxB genes encoding the arsenite oxidase large subunit was investigated. The distribution of bacterial aoxB genes is wider than what was previously thought. AoxB subfamilies characterized by specific signatures were identified. An exhaustive analysis of AoxB sequences from this study and from public databases shows that horizontal gene transfer has likely played a role in the spreading of aoxB in prokaryotic communities.
在这项研究中,从一个砷含量较高的环境(法国圣玛丽奥米讷)中分离出新的菌株,并研究了编码亚砷酸盐氧化酶大亚基的 aoxB 基因的多样性。细菌 aoxB 基因的分布比之前认为的要广泛。确定了具有特定特征的 aoxB 亚家族。对本研究和公共数据库中 AoxB 序列的全面分析表明,水平基因转移可能在 aoxB 在原核生物群落中的传播中发挥了作用。