Nat Cell Biol. 2011 Jun;13(6):638-9. doi: 10.1038/ncb2276. Epub 2011 May 15.
Aurora A kinase is a key regulator of cell division, whose functions were attributed to its ability to phosphorylate diverse substrates. Aurora A is now shown to have a kinase-independent role in the regulation of chromatin-mediated microtubule assembly.
极光激酶 A 是细胞分裂的关键调节因子,其功能归因于其磷酸化多种底物的能力。现在已经表明,极光激酶 A 在调节染色质介导的微管组装中具有激酶非依赖性作用。