Hardin Narayan Alison R, Sarpong Richmond
Department of Chemistry, University of California, Berkeley, California, 94720, USA.
Green Chem. 2010;12(9):1556-1559. doi: 10.1039/C0GC00198H.
Hetero-cycloisomerization reactions of propargylic alcohol derivatives leading to indolizines have been demonstrated to proceed in the presence of water alone. This stands as a significant advance over the previous methods using Pt, Cu or Ag salts paired with ligands in organic solvents such as benzene, acetonitrile or methylene chloride.
已证明，炔丙醇衍生物生成中氮茚的杂环异构化反应仅在水存在的情况下就能进行。与之前在苯、乙腈或二氯甲烷等有机溶剂中使用铂、铜或银盐与配体配合的方法相比，这是一个重大进展。
