Sachdeva Silonie, Sachdeva Shabina, Kapoor Pranav
Carolena Skin, Laser & Research Centre, Jalandhar, Punjab, India.
J Cutan Aesthet Surg. 2011 Jan;4(1):58-60. doi: 10.4103/0974-2077.79199.
Laugier-Hunziker syndrome (LHS) is an acquired, benign pigmentary skin condition involving oral cavity including lower lip in the form of brown black macules 1-5 mm in size, frequently associated with longitudinal melanonychia. There is no underlying systemic abnormality or malignant predisposition associated with LHS, and therefore the prognosis is good. Important differential diagnoses include Peutz Jeghers syndrome and Addison's disease among other causes of oral and acral pigmentation. Treatment is sought mainly for cosmetic reasons and Q-switched Nd-Yag laser/ Q-switched alexandrite therapy and cryosurgery have been tried with varying success.
劳吉尔-杭齐克尔综合征(LHS)是一种后天性良性色素沉着性皮肤病,累及口腔,以下唇出现大小为1-5毫米的棕黑色斑疹为表现形式,常伴有甲纵嵴黑甲。LHS不存在潜在的全身异常或恶性倾向,因此预后良好。重要的鉴别诊断包括黑斑息肉综合征和艾迪生病以及其他导致口腔和肢端色素沉着的病因。治疗主要是出于美容目的,已尝试使用调Q Nd:YAG激光/调Q翠绿宝石激光疗法和冷冻手术,效果各异。