Shah Samir S, Oh Catherine H, Coffin Susan E, Yan Albert C
Department of Pediatrics, Children's Hospital of Philadelphia, Pennsylvania 19104, USA.
Cutis. 2005 Aug;76(2):97-9.
Cutaneous pigmentation is a hallmark of Addison disease. When present, the hyperpigmentation generally localizes to sun-exposed surfaces. This case highlights a less well-recognized cutaneous feature that is pathognomonic for the disease: oral mucous membrane hyperpigmentation. We describe this unique type of discoloration in detail and contrast it with other forms of oral pigmentation.
皮肤色素沉着是艾迪生病的一个标志。若出现色素沉着,通常会出现在暴露于阳光下的部位。本病例突出了该病一种较少被认识的、具有诊断意义的皮肤特征:口腔黏膜色素沉着。我们详细描述了这种独特的色素沉着类型,并将其与其他形式的口腔色素沉着进行对比。